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                        Ascaridole

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                        • Ascaridole

                        Ascaridole is an oxide, as found in wormseed and boldo.  It is a toxic peroxide!

                        Oxides contribute to an oil’s aroma, and have strong therapeutic actions, but can be neurotoxic, liver toxic, and a respiratory irritant in excess.

                        Links to Plants Containing Ascaridole

                         


                        Research

                        The listings of research below represents a compilation of scientific articles found on the topic, with a very brief overview description of each article/study.  This compilation of research articles does not necessarily imply that there are adequate results to demonstrate safe and/or effective human use of any herb listed.

                        TOXIC

                        • This article discussed the toxicity of carvacrol, caryophyllene oxide, and ascaridole found in wormseed.  From:  Monzote, L., Stamberg, W., Staniek, K., & Gille, L. (2009). Toxic effects of carvacrol, caryophyllene oxide, and ascaridole from essential oil of Chenopodium ambrosioides on mitochondria. Toxicology and applied pharmacology, 240(3), 337-347.

                        ANTI-PARASITIC

                        • Ascaridole is a terpene isolated from Chenopodium ambrosioides (wormseed) and a known anthelmintic.  It was tested in vitro against the parasite, Plasmodium falciparum. From:  Pollack, Y., Segal, R., & Golenser, J. (1990). The effect of ascaridole on the in vitro development of Plasmodium falciparum. Parasitology Research, 76(7), 570-572.

                        By: Kathy Sadowski

                        Updated: 01/04/19

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