Calendula Wound Serum

calendula infusion

calendula infusion

Pictured: Calendula Infusion

By: Kathy Sadowski, Master of Science Degree in Aromatherapy, Registered Aromatherapist, LMT, RYT

Studies have shown calendula to be useful in treating wounds.  The following is a calendula wound serum recipe.  Research is listed below.

Calendula Wound Serum Ingredients:

  • 30 fresh organically grown calendula blossoms (Calendula officinalis)
  • 1 ounce of Vitamin E oil
  • 5 ounce of sweet almond oil
  • 10 drops of lavender essential oil

Instructions: Gently rinse blossoms and air dry for a day.  Place in a glass jar and pour sweet almond oil on top.  Seal with a lid.  Shake once a day for four weeks.  After four weeks, strain out blossoms using cheesecloth or a coffee filter.  Add Vitamin E oil and lavender to the strained oil.  Store in a sealed amber glass container for up to one year.  Apply the calendula wound serum to wounds, dry skin, and to prevent scaring.


  • Calendula improved skin elasticity, tightness, and hydration.  From:  Akhtar, N., Zaman, S. U., Khan, B. A., Amir, M. N., & Ebrahimzadeh, M. A. (2011). Calendula extract: effects on mechanical parameters of human skin. Acta Pol. Pharm, 68(5), 693-701.
  • Phenolic acids, flavonoids, sterols, terpenoids, and triterpenes are all compounds contained in C. officianalis with antioxidant and free radical reducing capabilities. From:  Alnuqaydan, A. M., Lenehan, C. E., Hughes, R. R., & Sanderson, B. J. (2015). Extracts from Calendula officinalis offer in vitro protection against H2O2 induced oxidative stress cell killing of human skin cells. Phytotherapy Research, 29(1), 120-124.
  • In folk medicine, calendula has been used for topical wound healing and inflammation.  From:  Arora, D., Rani, A., & Sharma, A. (2013). A review on phytochemistry and ethnopharmacological aspects of genus Calendula. Pharmacognosy reviews, 7(14), 179.
  • Topical application of C. officinalis can provide protection from oxidative stress and photo damage, healing damaged skin, and improved anti-aging.  From:  Bernatoniene, J., Masteikova, R., Davalgiene, J., Peciura, R., Gauryliene, R., Bernatoniene, R., … & Muselik, J. (2011). Topical application of Calendula officinalis (L.): Formulation and evaluation of hydrophilic cream with antioxidant activity. Journal of Medicinal Plants Research, 5(6), 868-877.
  • Flavonoids are antimicrobial and antioxidant, to help the skin fight infection. From:  Butnariu, M., & Coradini, C. Z. (2012). Evaluation of biologically active compounds from Calendula officinalis flowers using spectrophotometry. Chemistry Central Journal, 6(1), 1.
  • The author indicated the constituents acting as antioxidants in marigold are its carotenoids and flavonoids.  From:  Ćetković, G. S., Djilas, S. M., Čanadanović-Brunet, J. M., & Tumbas, V. T. (2004). Antioxidant properties of marigold extracts. Food Research International, 37(7), 643-650.
  • Wound healing was accelerated among patients with venous leg ulcers who used an ointment with C. officinalis From:  Duran, V., Matic, M., Jovanovć, M., Mimica, N., Gajinov, Z., Poljacki, M., & Boza, P. (2004). Results of the clinical examination of an ointment with marigold (Calendula officinalis) extract in the treatment of venous leg ulcers. International journal of tissue reactions, 27(3), 101-106.
  • The author(s) conducted a study demonstrating the potential for C. officinalis against skin UV irradiation induced oxidative stress.  From:  Fonseca, Y. M., Catini, C. D., Vicentini, F. T., Nomizo, A., Gerlach, R. F., & Fonseca, M. J. V. (2010). Protective effect of Calendula officinalis extract against UVB-induced oxidative stress in skin: Evaluation of reduced glutathione levels and matrix metalloproteinase secretion. Journal of ethnopharmacology, 127(3), 596-601.
  • The study demonstrated improved wound healing in rats with a blend of Hypericum perforatum (St. John’s Wart) and Calendula arvensis.  From:  Lavagna, S. M., Secci, D., Chimenti, P., Bonsignore, L., Ottaviani, A., & Bizzarri, B. (2001). Efficacy of Hypericum and Calendula oils in the epithelial reconstruction of surgical wounds in childbirth with caesarean section. Il Farmaco, 56(5), 451-453.
  • Women receiving radiation therapy for breast cancer showed improved healing of acute dermatitis with the use of 20% fresh marigold in petroleum jelly compared to trolamine.  From:  Pommier, P., Gomez, F., Sunyach, M. P., D’hombres, A., Carrie, C., & Montbarbon, X. (2004). Phase III randomized trial of Calendula officinalis compared with trolamine for the prevention of acute dermatitis during irradiation for breast cancer. Journal of Clinical Oncology, 22(8), 1447-1453.
  • The plant demonstrated anti-inflammatory and wound healing activity.  From:  Preethi, K. C., & Kuttan, R. (2009). Wound healing activity of flower extract of Calendula offlcinalis. Journal of basic and clinical physiology and pharmacology, 20(1), 73-80.
  • A combination of Cassia tora, Calendula officinalis, and Momordica charantia was antibacterial in treating psoriasis.  From:  Roopashree, T. S., Dang, R., Rani, R. S., & Narendra, C. (2008). Antibacterial activity of antipsoriatic herbs: Cassia tora, Momordica charantia and Calendula officinalis. International Journal of Applied research in Natural products, 1(3), 20-28.
  • Creams with rosemary and marigold reduced irritation contact dermatitis.  From:  Fuchs, S. M., Schliemann-Willers, S., Fischer, T. W., & Elsner, P. (2005). Protective effects of different marigold (Calendula officinalis L.) and rosemary cream preparations against sodium-lauryl-sulfate-induced irritant contact dermatitis. Skin pharmacology and physiology, 18(4), 195-200.
  • Calendula and its faradiol constituent demonstrated topical anti-inflammatory activity.  From:  Della Loggia, R., Tubaro, A., Sosa, S., Becker, H., & Isaac, O. (1994). The role of triterpenoids in the topical anti-inflammatory activity of Calendula officinalis flowers. Planta medica, 60(06), 516-520.
  • A supplement of beta carotene was protective against UV skin damage in humans.  From:  Heinrich, U., Gärtner, C., Wiebusch, M., Eichler, O., Sies, H., Tronnier, H., & Stahl, W. (2003). Supplementation with β-carotene or a similar amount of mixed carotenoids protects humans from UV-induced erythema. The Journal of nutrition, 133(1), 98-101.
  • A randomized comparative trial of 60 infants showed that a treatment with aloe vera and calendula was safe and effective in treating diaper rash.  From:  Panahi Y, Sharif MR, Sharif A, et al. A randomized comparative trial on the therapeutic efficacy of topical aloe vera and Calendula officinalis on diaper dermatitis in children. ScientificWorldJournal. 2012;2012:810234.


  • Patients had reduced inflammation level, ulcer size, healing time, and pain from recurrent aphthous ulcerations.  From:  Altaei, D. T. (2012). Topical lavender oil for the treatment of recurrent aphthous ulceration. American journal of dentistry, 25(1), 39-43.
  • This study suggested using lavender essential oil instead of Povidone-iodine topically for episiotomy wound care. From:  Vakilian, K., Atarha, M., Bekhradi, R., & Chaman, R. (2011). Healing advantages of lavender essential oil during episiotomy recovery: a clinical trial. Complementary therapies in clinical practice, 17(1), 50-53.