Carotol

Carotol is a sesquiterpene alcohol that makes up about 40% of carrot seed oil.

Links to Plants Containing Carotol

Carrot Seed Oil

RESEARCH

The listings of research below represent a compilation of scientific articles found on the topic, with a very brief overview description of each article/study.  This compilation of research articles does not necessarily imply that there are adequate results to demonstrate safe and/or effective human use of any herb listed.

ANTIMICROBIAL / ANTIBACTERIAL / ANTIFUNGAL

• Carrot seed carotol extract was the most effective against Gram-positive bacteria with carotol being the most significant constituent.  From: Glišić, S. B., Mišić, D. R., Stamenić, M. D., Zizovic, I. T., Ašanin, R. M., & Skala, D. U. (2007). Supercritical carbon dioxide extraction of carrot fruit essential oil: Chemical composition and antimicrobial activity. Food chemistry, 105(1), 346-352.
• Carrot seed essential oil and its carotl constituent showed antifungal activity against the rice fungi: Bipolaris oryzae and Fusarium moniliforme. From: Sharma, M. (2018). Isolation, derivatization of compounds from carrot seed oil and their antifungal potential (Doctoral dissertation, Punjab Agricultural University, Ludhiana).
• The strongest antifungal activity was observed for the main constituent of carrot seed oil, carotol.  From:  Jasicka-Misiak, I., Lipok, J., Nowakowska, E. M., Wieczorek, P. P., Młynarz, P., & Kafarski, P. (2004). Antifungal activity of the carrot seed oil and its major sesquiterpene compounds. Zeitschrift für Naturforschung C, 59(11-12), 791-796.

ANTICANCER

• Carotol showed moderate cytotoxicity on monkey kidney and human pharynx squamous cell carcinoma cell lines.  From: Sieniawska, E., Świątek, Ł., Rajtar, B., Kozioł, E., Polz-Dacewicz, M., & Skalicka-Woźniak, K. (2016). Carrot seed essential oil—Source of carotol and cytotoxicity study. Industrial Crops and Products, 92, 109-115.

REPELLENT

• In vitro and in vivo tests showed a carrot seed essential oil and the carotol constituent to be repellent against multiple tested mosquito species. From: Ali, A., Radwan, M. M., Wanas, A. S., & Khan, I. A. (2018). Repellent Activity of Carrot Seed Essential Oil and Its Pure Compound, Carotol, Against Mosquitoes. Journal of the American Mosquito Control Association, 34(4), 272-280.

GREEN GARDENING

• Carrot seed oil extracts as well as its constituents of carotol, daucene, and daucol were nematicidal against the plant parasite: Meloidogyne incognita. From: Kaur, A., Chahal, K. K., Kataria, D., Kumar, A., & Urvashi, B. (2018). Assesment of carrot seed essential oil and its chemical constitu‐ents against Meloidogyne incognita. Journal of Pharmacognosy and Phytochemistry, 7(1), 896-903.
• Carrot seed essential oil and its carotl constituent showed antifungal activity against the rice fungi: Bipolaris oryzae and Fusarium moniliforme. From: Sharma, M. (2018). Isolation, derivatization of compounds from carrot seed oil and their antifungal potential (Doctoral dissertation, Punjab Agricultural University, Ludhiana).

By: Kathy Sadowski

Updated: 7/22/19