Iridoids are monterpenoid glycosides as found in plants like plantain. It can also be found in the noni fruit. Common iridoids include aucubin and catalpol.
Links to Plants Containing Iridoids
The listings of research below represents a compilation of scientific articles found on the topic, with a very brief overview description of each article/study. This compilation of research articles does not necessarily imply that there are adequate results to demonstrate safe and/or effective human use of any herb listed.
ANTIMICROBIAL / ANTIBACTERIAL / ANTIVIRAL
- Aucubin, an iridoid glycoside suppressed hepatitis B virus DNA replication in vitro. From: Chang, I. M. (1997). Antiviral activity of aucubin against hepatitis B virus replication. Phytotherapy research, 11(3), 189-192.
- Iridoids from noni fruit demonstrated antimicrobial activity against multiple tested bacteria. From: West, B. J., Palmer, S. K., Deng, S., & Palu, A. K. (2012). Antimicrobial activity of an iridoid rich extract from” morinda citrifolia” fruit. Current Research Journal of Biological Sciences, 4(1), 52-54.
- P. major, and its constituents baicalein, and aucubin inhibited reactive oxygen species production by human neutrophils and may be useful in treating periodontal conditions. From: Reina, E., Al-Shibani, N., Allam, E., Gregson, K. S., Kowolik, M., & Windsor, L. J. (2013). The effects of plantago major on the activation of the neutrophil respiratory burst. Journal of traditional and complementary medicine, 3(4), 268-272.
- Aucubin showed high liver-protective activity against hepatic damage in mice and showed a potent antidotal effects on beagle dogs with mushroom poisoning. From: Chang, I. M. (1998). Liver-protective activities of aucubin derived from traditional oriental medicine. Research communications in molecular pathology and pharmacology, 102(2), 189-204.
Compiled by: Kathy Sadowski