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                        Oleuropein

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                        • Oleuropein

                        Oleuropein is a phenol ethanol as found in olive leaves.

                        Links to Plants Containing Oleuropein

                         


                        RESEARCH

                        The listings of research below represents a compilation of scientific articles found on the topic, with a very brief overview description of each article/study.  This compilation of research articles does not necessarily imply that there are adequate results to demonstrate safe and/or effective human use of any herb listed.

                        ANTIOXIDANT

                        • This study attributed antioxidant activity of olive leaves to its high oleuropein content.  From:  Le Tutour, B., & Guedon, D. (1992). Antioxidative activities of Olea europaea leaves and related phenolic compounds. Phytochemistry, 31(4), 1173-1178.
                        • Olive leaf and its phenolic constituents have antioxidant and antimicrobial activity.  From:  Lee, O. H., & Lee, B. Y. (2010). Antioxidant and antimicrobial activities of individual and combined phenolics in Olea europaea leaf extract. Bioresource technology, 101(10), 3751-3754.
                        • Oleuropein showed antioxidant activity.  From:  Visioli, F., Bellosta, S., & Galli, C. (1998). Oleuropein, the bitter principle of olives, enhances nitric oxide production by mouse macrophages. Life sciences, 62(6), 541-546.

                        ANTIMICROBIAL

                        • Opeuropein showed activity against microbes causing intestinal or respiratory tract infections in man.  From:  Bisignano, G., Tomaino, A., Cascio, R. L., Crisafi, G., Uccella, N., & Saija, A. (1999). On the in‐vitro antimicrobial activity of oleuropein and hydroxytyrosol. Journal of pharmacy and pharmacology, 51(8), 971-974.

                        ANTIDIABETIC

                        • The study shows that both oleuropein and oleanolic acid are involved in the anti-diabetic effect of olive leaves.  From:  Sato, H., Genet, C., Strehle, A., Thomas, C., Lobstein, A., Wagner, A., … & Saladin, R. (2007). Anti-hyperglycemic activity of a TGR5 agonist isolated from Olea europaea. Biochemical and biophysical research communications, 362(4), 793-798.
                        • Oleuropein inhibiting hyperglycemia and oxidative stress induced by diabetes in rabbits.  From:  Al-Azzawie, H. F., & Alhamdani, M. S. S. (2006). Hypoglycemic and antioxidant effect of oleuropein in alloxan-diabetic rabbits. Life sciences, 78(12), 1371-1377.

                        By: Kathy Sadowski

                        Updated:1/12/19

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