Valerenic acid is a sesquiterpenoid found in valerian.
Links to Plants Containing Valerenic Acid
The listings of research below represents a compilation of scientific articles found on the topic, with a very brief overview description of each article/study. This compilation of research articles does not necessarily imply that there are adequate results to demonstrate safe and/or effective human use of any herb listed.
Valerenic acid from valerian root had a sedative effect in mice. From: Hendriks, H., Bos, R., Woerdenbag, H. J., & Koster, A. S. (1985). Central nervous depressant activity of valerenic acid in the mouse. Planta medica, 51(01), 28-31.
Valerian had a sedative effect on rat brain. From: Yuan, C. S., Mehendale, S., Xiao, Y., Aung, H. H., Xie, J. T., & Ang-Lee, M. K. (2004). The gamma-aminobutyric acidergic effects of valerian and valerenic acid on rat brainstem neuronal activity. Anesthesia & Analgesia, 98(2), 353-358.